Acne vulgaris (an inflammatory skin disease) Treatment
Acne vulgaris is a chronic inflammatory disease of the sebaceous glands, It's usually associated with a high rail of sebum secretion and occurs on areas of the body that have sebaceous glands, such as the face, neck, chest, back, and shoulders. Excessive sebum is usually secreted into the dilated hair follicles. The sebum joins with the bacteria and keratin in the hair follicles to form a plug. There are two types of acne:
Acne vulgaris develops in approximately 85% of the population, primarily between ages 15 and 18. Although the lesions can appear as early as age 8 or as late as age 58, acne primarily affects adolescents. Although the severity and overall incidence of acne is usually greater in males, it tends to start at an earlier age and last longer in females.
Causes of Acne vulgaris
The cause of acne is multifactorial. Although many myths exist that chocolate or fatty foods may cause acne, studies have shown that diet isn't a precipitating factor. Possible causes of acne include increased activity of sebaceous glands and blockage of the pilosebaceous ducts (hair follicles).
Factors that may predispose one to, acne include:
Signs and symptoms
The acne plug may appear as:
Rupture or leakage of an enlarged plug into the epidemics produces inflammation, characteristic acne pustules, papules or, in severe forms, acne cysts or abscesses (chronic, recurring lesions producing acne scars).
In women, signs and symptoms may include increased severity just before or during menstruation when estrogen levels are lowest.
Complications of acne may include:
Diagnosis is confirmed by characteristic acne lesions. especially in adolescents. Additionally, a culture may be taken to identify a Possible secondary bacterial infection. which may present as an exacerbation of pustules or abscesses while on tetracycline or erythromycin drug therapy.
Benzoyl peroxide (Benzac 5 or 10) is the treatment of choice for noninflammabled lesions; it may also be used for milder forms of inflamed lesions. However, for more severe inflamed acne, treatment should include the application of antibacterial agents, such as clindamycin, or benzoyl peroxide plus erythromycin (Benzamycin) antibacterial agents. These may applied alone or with tretinoin (Retetin-A; retinoic acid), which is a keratolytic. Keratolytic agents, such as benzoyl peroxide and tretinoin, dry and peel the skin in order to help open blocked follicles, moving the sebum up the skin level.
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